Mechanical Code…
Made up of a letter (A or B), that indicates the toxicity class, followed by a number (1, 2, or 3), that indicates the flammability class. Refrigerant blends are similarly classified, based on the compositions at their worst cases of fractionation, as separately determined for toxicity and flammability. In some cases, the worst case of fractionation is the original formulation.
Toxicity
Classes A and B signify refrigerants with “lower toxicity” and “higher toxicity,” respectively, based on prescribed measures of chronic (long-term, repeated exposures) toxicity.
Flammability
Class 1 indicates refrigerants that do not show flame propagation in air when tested by prescribed methods at specified conditions. Classes 2 and 3 signify refrigerants with “lower flammability” and “higher flammability,” respectively. The distinction depends on both the Lower Flammability Limit (LFL) and heat of combustion.
(Uniform Mechanical Code® 220.0)